MULTI-RESPONSE AND MULTI-CRITERIA OPTIMIZATION OF ACID HYDROLYZATE DETOXIFICATION OF COCOA POD HUSKS: EFFECT ON THE CONTENT OF PHENOLIC COMPOUNDS AND FERMENTABLE SUGARS

Dilute acid hydrolysis is the most common and effective method for converting lignocellulosic substrates into fermentable sugars.However, this hydrolysis partially degrades the lignin into phenolic compounds (PC), inhibiting the fermentation medium by retaining it in read more the hydrolyzate.Response surface methodology is a modeling and optimizat

Crambescins are guanidine alkaloids from the sponge Crambe crambe.Crambescin C1 (CC) induces metallothionein genes and nitric oxide (NO) is one of the triggers.We studied and compared the in vitro, in vivo, and in silico effects of some crambescine A and C analogs.HepG2 gene expression was analyzed using microarrays.Vasodilation was studied in rat

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